Google+ Twitter Facebook Facebook Previous articleVehicle crashes into Zolman Tire in MishawakaNext articleBiden endorsement from Oliver Davis Jr. Associated PressNews from the Associated Press and its network of reporters and publications. Pinterest Kendallville police officer shoots suspect during struggle By Associated Press – November 23, 2019 0 344 Google+ (“Police car lights” by Scott Davidson, Attribution 2.0 Generic) KENDALLVILLE, Ind. (AP) — Authorities say a northeastern Indiana police officer struggling with a domestic violence suspect shot and wounded the man after he pulled a handgun from his waistband.Indiana State Police say the shooting occurred about 8 a.m. Friday at a home in Kendallville.Police say the Kendallville officer arriving first at the home contacted the man and a struggle ensued outside. When the man produced the handgun, the officer fired his service weapon.Police say the suspect was taken to a Fort Wayne hospital for treatment. The extent of his injuries wasn’t clear. The officer wasn’t hurt.State police are investigating the shooting. Pinterest Twitter WhatsApp WhatsApp IndianaNews
AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore A newly-adopted dog out for a walk, suddenly bolted, pulling his owner for a half mile down the street arriving at a baby on the ground who wasn’t breathing. The Florida woman then proceeded to revive the baby with CPR, while her frantic mother said the child had been drowning in the bath tub. It turns out the dog had been trained in child rescue but hadn’t passed the course, and was put up for adoption! Watch the incredible KVVU report below, or at Clip Syndicate… AddThis Sharing ButtonsShare to FacebookFacebookFacebookShare to TwitterTwitterTwitterShare to EmailEmailEmailShare to RedditRedditRedditShare to MoreAddThisMore
In celebration of the 25th anniversary of the fall of the Berlin Wall, the Kroc Institute for International Peace Studies and the Nanovic Institute for European Studies sponsored a faculty panel Tuesday in the Hesburgh Center for International Studies to discuss the significance of the events in 1989 in Eastern Europe and their importance to international affairs today.The panel featured A. James McAdams, professor of international affairs and Director of the Nanovic Institute for European Studies; David Cortright, associate director of programs and policy studies of the Kroc Institute for International Peace Studies; Sebastian Rosato, associate professor of political science and director of the Notre Dame International Security Program and Alicja Kusiak-Brownstein, adjunct professor of history.McAdams began the panel, chronicling the history of the fall of the Wall and the suddenness with which it occurred.“We can say that it [the wall] fell but in a way, what it did was open,” he said. “The border that had meant certain death if you tried to run across it in the past, that had meant certain imprisonment if you tried to smuggle your way through it in the past … that border ceased to exist.”The fall of the Wall was met with joy but also confusion, McAdams said.“What is so important to understand at this time is the way in which everyone was surprised, everyone was shocked,” he said. “No one had any idea what this meant.”The political implications of the fall of the Wall also opened up a lot of questions as to what the next step was, McAdams said.“The big question was what happens when the division between East and West, that was defined by the Berlin Wall, more than any other entity, what happens when that division is gone?” he said. “What happens when you suddenly have to deal with a reunified Germany?”The fall of the Wall, Cortright said, cannot be traced to one single individual, institution or state.“Whenever there’s a great success, it is said, success has many parents, while failure is orphaned,” Cortright said. “In this case, there are many claims to success. Margaret Thatcher says it was Ronald Reagan who won the Cold War; Reagan says it was Thatcher who won the Cold War.“Even some East German communists thought it was their idea. Pope John Paul II played a big role, and Gorbachev definitely.”However, the most important force in this kind of success is civil society, Cortright said.“It’s inconceivable to think of the fall of the Wall or the dramatic transformations that took place in the late ’80s without understanding the role of civil society and the tremendous push that was created by the people in the street, protesting against the Communist regime,” he said.Cortright said disarmament played a large role in ending the Cold War but not in the way that many would think. Rather, disarmament talks led to a more benign relationship between the Soviet Union and the United States.“It was the transformation of the politic climate and the opening of the new political leadership in the Soviet Union, represented by Gorbachev, that really led to the end,” he said. “… It was not about the weapons, but the development of a political understanding between the United States and the Soviet Union.”Kusiak-Brownstein, who hails from Poland, shared personal accounts from both herself and her friends on the fall of the Wall.“One friend said she was preparing for her finals in high school when her mother came in her room and said, ‘You’ll never believe it. The Berlin Wall has fallen.’ My friend answered, ‘It’s about time, isn’t it?’” she said.Many of the people in Poland reacted in this way because Poland had already gone through a political transformation in the spring of 1989, Kusiak-Brownstein said.“The fall of the Wall followed the first semi-free election in Poland, which resulted in overwhelming support for the opposition,” she said. “In spite of it, among young people, the spirit of euphoria was often mixed with anxiety.”The consequences of the fall of the Wall were felt far beyond just Eastern Europe and still continue to reverberate today, Rosato said.“The fall of the Wall led to a U.S. strategy of what can be called liberal primacy,” he said. “Primacy, because the United States was determined to remain the most powerful state in the world for as long as possible, which meant, at the time, basically preventing the return of Russia and Western Europe, especially Germany, becoming powerful.“Liberal, because the United States wanted to spread liberal values all across the globe: democracy, free markets, etc. The reason for that is because one, it would make America safe and two, it was the right thing to do.”The results of this strategy, however, have been a huge disappointment, Rosato said.“This strategy of the US has three failures,” he said. “It guaranteed that the [European Union] would be a geopolitical nonentity; it threatened Russia by encircling it and seeking to destabilize it.“Third, we not only threatened Russia, but antagonized Russia by extending NATO all the way up to its border and making it pretty clear that Russia is next.”This strategy and its failures, stemming from the fall of the Wall, play a huge part in international politics today, demonstrating the far-reaching consequences and importance of the fall of the Wall, Rosato said.Tags: Berlin, Berlin Wall, Cold War, Eastern Europe, germany, Nanovic Institute, Russia
Three more leaders in demand response and smart grid have joined the Association for Demand Response and Smart Grid (ADS), the national DR and smart grid organization. They come aboard as ADS, together with other national groups, prepares for next week’s National Summit on Integrating Energy Efficiency and Smart Grid (www.energyefficiencysmartgrid.org(link is external)). The new members are Olivine, Inc, Vermont Energy Investment Corporation (VEIC), and EnergyHub.ADS is a non-profit organization based in Washington, DC, that focuses on development and exchange of information among policymakers, utilities, technology companies, and other stakeholders. It includes as members companies and organizations, as well as individuals who consider themselves demand response (DR) and smart grid professionals.”We are excited to have these new members join ADS and help us grow our ability to serve the needs of the DR and smart grid community,” said Dan Delurey, Executive Director of ADS. “Olivine offers a number of options to support DR in the wholesale market, and is also a DR provider and scheduling coordinator. VEIC is a great asset to the discussion on how best to integrate energy efficiency with demand response as they have a strong focus on reducing the overall costs of energy use. And EnergyHub offers in-home options to consumers for reducing their energy using a variety of resources.”We are especially happy to have these new members come on board as we ramp up for the National Summit on Integrating Energy Efficiency and Smart Grid,” said Delurey. “They have already begun to help us as we make final preparations for the event coming up October 15 and 16.” Olivine, Inc. supports responsible demand, by delivering technology, operations, programs, and consulting services in an innovative wrap-around approach to tackle all sides of a problem from regulatory to implementation down to consumer use cases. This approach, part of the Olivine Wayâ ¢, allows Olivine to make a bigger impact by ensuring ultimate value in the projects we undertake. For more information, visit http://olivineinc.com/(link is external). EnergyHub develops software solutions that allow utilities to operate more effective demand response and energy efficiency programs than ever before. EnergyHub’s Mercury DRMS features utility-grade security and robustness, and it runs on a platform that was built from the ground up for real-time massive data processing. EnergyHub’s Bring Your Own Thermostat℠ service means hundreds of thousands of homes are reachable without the need to roll a single truck. For more information, visithttp://www.energyhub.com/(link is external).Vermont Energy Investment Corporation (VEIC) is dedicated to reducing the economic and environmental costs of energy use. Through its comprehensive energy efficiency utilities and implementation and consulting services, it works with utilities, government agencies, and foundations in the design and delivery of energy efficiency and renewable energy services. VEIC sees electric system planning, market operations, and regulatory policy-making as three interconnected approaches to transforming the energy system. VEIC’s planning engineers specialize in state and regional demand-side planning and understanding the potential of renewable resources. And its program implementation staff uses these studies to develop economic strategies for wholesale power markets. These insights enable VEIC to provide decision-makers with fresh, timely recommendations that are grounded in real-world engineering and economic feasibility. The result is innovative programs, policies, and implementation strategies that promote the highest levels of reliability, affordability, and efficiency. For more information, visit http://www.veic.org/(link is external).About the Association for Demand Response & Smart GridThe Association for Demand Response & Smart Grid (ADS) is a nonprofit organization, originally formed as the Demand Response Coordinating Committee (DRCC) in 2004. ADS is a 501 (c) 3 nonprofit organization consisting of professionals and organizations involved in demand response and smart grid. It provides services to meet the needs of its members that help them in the conduct of their work and in the attainment of their personal, corporate and governmental objectives. ADS seeks to establish and grow a demand response “community” of policymakers, utilities, system operators, technology companies, consumers, and other stakeholders.Group Members of ADS are Ameren, American Public Power Association, Arizona Public Service, California ISO, Comverge, Con Edison, Conservation Services Group, Constellation, Corporate Systems Engineering, Dimplex, Duke Energy, Emerson Climate Technologies, ENBALA, Energate, EnergyHub, EnerNOC, Freeman, Sullivan & Co, GE, ISO New England, Landis+Gyr, MISO, National Grid, National Rural Electric Cooperative Association, Navigant Energy Practice, Negawatt, NYSERDA, Olivine, Inc., On-Ramp Wireless, OPower, Pacific Gas & Electric, PECO, PJM Interconnection, Reliant, Rodan Energy Solutions, Inc., San Diego Gas & Electric, Siemens, Silver Spring Networks, Southern California Edison, Southern Company, Steffes Corporation, Tennessee Valley Authority, Vermont Energy Investment Corporation. More information on ADS can be found at: www.demandresponsesmartgrid.org(link is external)SOURCE WASHINGTON, Oct. 7, 2013 /PRNewswire-USNewswire/ — Association for Demand Response & Smart Grid
World Learning/SIT,Vermont Business Magazine School for International Training has received accreditation for its milestone EdD in Global Education(link is external), SIT Graduate Institute’s first doctorate, as well as the first degree of its kind offered by a US-based higher education institution. This new degree program deepens SIT’s dedication to advancing international education and positions the institution to play a vital role in shaping the field for years to come. “This is a historic moment for SIT and the next step for international education studies in the United States,” said Dr. Sophia Howlett, president of SIT. “At a time when thinking about internationalization seems so problematic, SIT leads the way once again. Our new doctorate is a statement of our belief in and commitment to the future of international education and will allow us and our students to be at the forefront of that future. We have a bold vision for SIT Graduate Institute and with the commitment, hard work, and passion of our faculty and staff, we are making it a reality.” The Vermont-based SIT Graduate Institute received its accreditation from the New England Commission of Higher Education, the regional accreditation agency responsible for colleges and universities in New England. The three-year, 60-credit doctorate is a part-time hybrid degree delivered online with brief, summer residencies on SIT’s campus in Brattleboro, Vermont. “I’m so pleased we are adding SIT’s first doctoral program to our portfolio of accredited degrees,” said Dr. Alla Korzh, chair of the EdD in Global Education. “This unique program provides an opportunity for professionals who are passionate about education in their local and global communities to advance their leadership in the field and conduct in-depth research that will help address education issues around the world.” The EdD program, draws from SIT’s unique brand of in-depth, reflective practice and intensive research training. It allows students to pursue their own specializations in education at any level, in any subfield, in any location. The program offers deeply immersive doctoral seminars; case studies; theory; data collection; research methods; written projects and reflective practice tied to students’ ongoing work experience. Throughout the program students will receive one-on-one guidance from SIT advisors who will work closely with doctoral students as they develop research topics of their choice and work toward their dissertation. SIT Graduate Institute is currently accepting applications for the first cohort of the EdD in Global Education(link is external) through November 1, 2020. Prospective students interested in learning more about admission to new EdD program can visit SIT Graduate Institute’s website(link is external) or contact the Admissions team by emailing [email protected](link sends e-mail) or calling 800.336.1616 (inside the U.S) or +1.802.258.3150 (outside of the U.S.). Visit our website(link is external) to learn more about SIT Graduate Institute programs and scholarships. SIT is part of the World Learning Inc. family(link is external), a global NGO that advances education, development, and cultural understanding around the world. Source: School for International Training 10.9.2020
The Union Cycliste Internationale (UCI) and Oakley have announced a two-year partnership starting in 2019. Under the deal, Oakley will support the UCI Mountain Bike World Championships presented by Mercedes-Benz and the Mercedes-Benz UCI Mountain Bike World Cup as an Official Partner.According to UCI, the arrival of the celebrated US eyewear brand, which is owned by the Italian group Luxottica and has been a player in the cycling industry for several decades now, is ‘yet another sign of the faith that leading brands and media partners have in mountain bike.’The 2018 Mercedes-Benz UCI Mountain Bike World Cup attracted record audiences on Red Bull TV, while there was a significant increase in the cumulative audience for the 2018 UCI World Championships in Lenzerheide (SUI), with 46 million viewers tuning in.Oakley has been part of the sport of cycling for more than three decades. In the 1980s, the brand made a name for itself within the road cycling peloton with its glasses, helmets and its line of clothing. Today it supplies several UCI WorldTeams and top teams in the UCI Women’s WorldTour.At the end of the 1990s, Oakley extended its activities to include mountain bike, and has been chosen by MTB legends such as Julien Absalon and Nino Schurter (cross-country Olympic) and Greg Minnaar and Rachel Atherton (downhill).“The arrival of an international brand such as Oakley is excellent news for mountain bike,” said UCI President David Lappartient. “At a time when our competitions are enjoying increasing popularity, it gives me great pleasure to see an established player in the cycling industry demonstrate their faith in our discipline. Our partnership will combine the global and high-profile exposure of UCI events with the expertise of Oakley products.”Ben Goss, Oakley Global Brand Director added, “At Oakley we look for partnerships that share our passion for technological innovation, that allow us to stay ahead of the game and set the standard in sports performance. We can’t wait to work with the UCI over the next two years and beyond in creating the ultimate experience for athletes and spectators.”Founded in 1900, in Paris (France), the Union Cycliste Internationale (UCI) is the worldwide governing body for cycling. It develops and oversees cycling in all its forms, for all people as a competitive sport, as a healthy recreational activity, as a means of transport, and also just for fun.UCI manages and promotes the nine cycling disciplines: road, track, mountain bike, BMX – racing and freestyle – paracycling, cyclo-cross, trials and indoor cycling. The UCI Mountain Bike World Cup was founded in 1991. Olympic cross-country and downhill competitions have since been held on several continents and across different age groups.www.uci.orgwww.oakley.com Related
Ethics opinion deals with representing county commissioners before the Ethics Commission Ethics opinion deals with representing county commissioners before the Ethics Commission August 15, 2006 Regular News The Board of Governors has issued Proposed Advisory Opinion 77-30 (Reconsideration) reprinted below. Pursuant to Rule 6(d) and (e) of The Florida Bar Procedures for Ruling on Questions of Ethics, comments from Florida Bar members are solicited on the proposed opinion. The board will consider any comments received at a meeting to be held on September 29 in Ponte Vedra. Comments must contain the proposed advisory opinion number and clearly state the issues for the board to consider. A written argument may be included explaining why the Florida Bar member believes the board’s opinion is either correct or incorrect and may contain citations to relevant authorities. Comments should be submitted to Elizabeth Clark Tarbert, Ethics Counsel, The Florida Bar, 651 E. Jefferson Street, Tallahassee 32399-2300, and must be postmarked no later than 30 days from the date of this publication. PROPOSED ADVISORY OPINION 77-30 (Reconsideration) (July 28, 2006) The Florida Bar Board of Governors has revised Florida Ethics Opinion 77-30 to clarify its views on conflicts involving a county attorney’s representation of a county commissioner charged with ethics violations before the Florida Commission on Ethics. In the 1978 opinion, the Professional Ethics Committee gave its opinion on the following circumstances: A county commissioner is charged before the ethics commission with misuse of public office in directing county employees to work on private property during normal working hours with county road equipment. The subject commissioner asks the county attorney to represent him as legal counsel. The county attorney is on contract with the county and engages in the private practice of law in addition to his work for the county. The committee found that the “situation represents an inherent conflict and the appearance of impropriety.” The committee’s opinion was based on the disciplinary rules and ethical canons. Since the opinion was written, the Rules Regulating The Florida Bar were adopted. Rule 4-1.7 states as follows: (a) Representing Adverse Interests. Except as provided in subdivision (b), a lawyer shall not represent a client if: (1) the representation of 1 client will be directly adverse to another client; or (2) there is a substantial risk that the representation of 1 or more clients will be materially limited by the lawyer’s responsibilities to another client, a former client or a third person or by a personal interest of the lawyer. (b) Notwithstanding the existence of a conflict of interest under subdivision (a), a lawyer may represent a client if: (1) the lawyer reasonably believes that the lawyer will be able to provide competent and diligent representation to each affected client; (2) the representation is not prohibited by law; (3) the representation does not involve the assertion of a position adverse to another client when the lawyer represents both clients in the same proceeding before a tribunal; and (4) each affected client gives informed consent, confirmed in writing or clearly stated on the record at a hearing. The board has heard from both the Florida Commission on Ethics, which has indicated that individual commissioners are frequently represented by a local government lawyer despite the opinion’s existence, and from the City, County and Local Government Law Section, which believes that the opinion is overbroad.The board agrees with the City, County and Local Government Law Section that the opinion may be overbroad, particularly the following statement: A county attorney represents the county commission, not the individual members serving on it. He places his responsibility as county attorney in jeopardy when he accepts an engagement to represent a particular commissioner before the Florida Ethics Commission. A county attorney may be required to represent individual commissioners by ordinance or charter or by contract with the county. Florida statutes also require particular governmental entities to provide representation to individual constituents in certain circumstances. See, e.g., Florida Statutes §§ 111.065 and 111.07. It is a legal and factual question, outside the scope of an ethics opinion, whether a county attorney is required to represent individual commissioners.The board is of the opinion that some conflicts involving individual county commissioners may be waived by both the individual commissioner and the county. For example, if a frivolous ethics complaint is filed against an individual commissioner and the county attorney can readily determine that the allegations are unfounded, the county attorney may represent the individual commissioner if both the individual commissioner and the county give informed consent, confirmed in writing, to the dual representation. Someone other than the individual commissioner to be represented must give informed consent on behalf of the county. Rule 4-1.13(e), Rules of Professional Conduct. Whether a county attorney may represent an individual commissioner in a particular ethics complaint will depend on the circumstances of the individual situation, and such an analysis must occur on a case by case basis.
What does Maryland need to do to upset the No.17 ranked Gophers?I think it comes down to pass rush and affecting the quarterback. It doesn’t necessarily need to include sacks, but if Tanner Morgan has time to sit back and watch Bateman and Johnson run routes, it’ll be a long day for Maryland’s defense. Of course, the Terps’ offense needs to put together more this week than it has recently, but the potential returns of running back Anthony McFarland Jr. and quarterback Josh Jackson could be a big boost.Best Offensive Player: Anthony McFarland Jr.Best Defensive Player: Antoine Brooks Jr.Under-The-Radar Player: Chance CampbellEnd of season record prediction: 4-8Score Prediction: 42-17, Minnesota Questions from the other side: MarylandThis week the Minnesota Daily caught up with Andy Kostka from The Diamondback. John MillerOctober 22, 2019Jump to CommentsShare on FacebookShare on TwitterShare via EmailPrintBefore every home game, The Minnesota Daily chats with a reporter who covers the opponent. This week, the Daily interviewed Andy Kostka from The Diamondback, the student newspaper at the University of Maryland.Maryland is 3-4 so far on the season, what’s the general vibe of the football team? Is that record indicative how the team really is? Are they worse or better than their record?Maryland football has a consistency problem, be it with its passing game or defense. In wins, its pass rush is imposing and offensive production explosive. But in those four losses, the Terps don’t bring the quarterback down, allow oodles of yards — they’ve surrendered more than 500 yards three times this season — while struggling to move the ball much on offense. So, 3-4 is a pretty fair place to be at the moment considering how Maryland’s played. And with the meat of its Big Ten schedule coming up, finding three wins for bowl eligibility will be quite a tough task.Against every Big Ten team this year besides Rutgers, the Maryland defense has given up 30-plus points. How can Maryland stop the potent offense of Minnesota? Or can they?I truly don’t believe Maryland can contend with Minnesota’s offense, particularly in the passing game against Rashod Bateman and Tyler Johnson. The Terps have allowed more than 300 passing yards to four opponents so far — Syracuse, Penn State, Purdue and Indiana — and quarterbacks Sean Clifford and Jack Plummer earned Big Ten Offensive Player of the Week honors after torching Maryland’s secondary. The Terps have dealt with injuries in the secondary, with Tino Ellis out for the year and Marcus Lewis missing two games with a knee injury, forcing freshmen Lavonte Gater and Deonte Banks into larger roles. There’s been a learning curve.Maryland seemed to land a big fish last December when they lured away Nick Saban’s co-offensive coordinator Michael Locksley to be their head coach, and he was the 2018 Broyles Award winner — given to the top assistant coach. How are fans feeling about him in year one? Does he seem to be the right guy for the program?Despite holding a 3-31 lifetime head coaching record before taking over Maryland on a full-time basis this offseason, there was quite a lot of excitement around Mike Locksley’s hiring, particularly because of his success as Alabama’s offensive coordinator. Perhaps some fans’ expectations were a touch too high entering the year, however. He had minimal time to recruit for this season and inherited much of the roster, so I’m not surprised by some of the issues this year. I’ll reserve more judgement on if Locksley is the right one to turn Maryland around until after his second season, when he’s had more time to imprint his style on things.
More MERS cases reported in Saudi Arabia, all linked to camelsAccording to updates posted this weekend and through today, Saudi Arabia has three more MERS-CoV cases, including two in Wadi ad-Dawasir.On Feb 16 the Ministry of Health (MOH) recorded two new cases of MERS-CoV (Middle East respiratory syndrome coronavirus) for epidemiologic week 7, including in a 65-year-old man from Wadi ad-Dawasir who had camel contact. That patient is currently hospitalized. The MOH also said a 78-year-old man from the Tabuk region also contracted the virus after camel contact. That patient died.Today the MOH recorded a case in a 53-year-old man from Wadi ad-Dawasir, the first in epidemiologic week 8. The patient also had camel contact and is hospitalized for his infection.The Saudi MOH has now confirmed 65 MERS infections since Jan 1, with 41 of those cases recorded in Wadi ad-Dawasir. Feb 16 MOH update Feb 18 MOH update CDC confirms 6 new acute flaccid myelitis casesThe US Centers for Disease Control and Prevention (CDC) reported 5 new cases of the polio-like condition known as acute flaccid myelitis (AFM) for last year and 1 new case for 2019, according to an update today.The newly reported 2018 cases raise last year’s numbers to 215 cases. The 215 cases are among 371 reports of PUIs (patients under investigation) and constitute the highest annual total the CDC has ever recorded. “So far in 2019, there have been 11 reports of PUIs, one of which has been confirmed (from North Carolina,)” the CDC said in its biweekly update on the mysterious disease dated Feb 15. “CDC and state and local health departments are still investigating some of the PUIs. CDC is not aware of any deaths in confirmed AFM cases with illness onsets in 2018 or 2019.”Texas has reported the most AFM cases, with 29. Colorado has 16 cases, Ohio has 14, and Washington state and California have 11. Minnesota, Pennsylvania, and New Jersey have each recorded 10.AFM activity tends to spike in an every-other-year pattern. The CDC first started tracking the disease in August of 2014, and that portion of the year saw 120 cases. In 2015 the agency confirmed 22 cases, in 2016 there were 149, and 2017 saw 35 cases.AFM affects the spinal cord, leaving patients—almost always children—with partial or total limb paralysis or muscle weakness. The cause of the disease is unknown, but 90% of patients report upper respiratory virus symptoms in the weeks prior to limb weakness. In previous years the syndrome has been tied to enterovirus infections. Feb 15 CDC update H9N2 avian flu infects one more person in ChinaChina has reported another H9N2 avian flu illness, which involves an 8-year-old from Yunnan province, according to a Macao Health Bureau statement translated and posted by Avian Flu Diary (AFD), an infectious disease news blog.The girl’s symptoms began on Jan 27, and she reportedly has a mild infection, which fits the typical pattern for H9N2. The strain is endemic in Chinese poultry, and exposure to poultry is a known risk factor in sporadic human illnesses.China reported seven cases in 2018, including one noted in early February in a boy from Hunan province whose symptoms began in late December.Feb 16 AFD post Study finds influenza A patients sicker for longer compared with flu BA study to gauge the difference in illness severity between influenza A and influenza B in hospitalized patients found that people infected by influenza A were sicker and recovered more slowly, researcher from China reported late last week in Open Forum Infectious Diseases.The observational study included adult patients admitted to China-Japan Friendship Hospital in Beijing with lab-confirmed seasonal flu from Oct 1, 2016, to Jun 1, 2018. In line with treatment guidance, patients were usually treated with neuraminidase inhibitors if they sought care or were hospitalized within 48 hours of illness onset. The team collected clinical data and rated clinical outcome on a seven-category scale that ranged from discharge with normal activity to death.Of 574 patients included in the study, 369 (64.3%) had influenza A and 205 (35.7%) had influenza B. On admission, patients with influenza A had worse clinical symptoms. By day 28, 82.4% of patients with influenza A had improved, compared with 90.7% of patients with influenza B. Also, patients with influenza B had a higher clinical improvement probability compared with those with influenza A (adjusted hazard ratio, 1.266; 95% confidence interval, 1.019 to 1.573; P = 0.0335). The researchers saw similar patterns for weaning supplemental oxygen, and they found that hospital mortality for influenza A was slightly higher than for influenza B—11.4% versus 6.8%.When the researchers adjusted for confounding factors such as time of initial antiviral treatment, age, and underlying diseases, they found the same results.They said the findings need to be validated by multicenter studies and added that their study wasn’t designed to detect differences among the two influenza A strains or the two influenza B lineages.Feb 15 Open Forum Infect Dis abstract H3N2 human challenge yields key data for developing vaccinesA human challenge study using seasonal H3N2 flu virus, the first of its kind to be grown in mammalian cells and produced with reverse genetics, found that it can be administered safely to produce mild-to-moderate disease, a key step in developing and evaluating better and more broadly protective flu vaccines.A team based at the National Institutes of Allergy and Infectious Diseases (NIAID) clinical studies unit reported its findings in Clinical Infectious Diseases.Of 49 healthy adults younger than 50 who were enrolled in the study from December 2015 through July 2017, 37 were included in the analysis. Patients were inoculated intranasally in a stepwise fashion. The researchers monitored viral shedding, symptoms, and immune responses. Of those challenged, 16 (43%) had viral shedding and 27 (73%) developed symptoms, 12 (32%) of them with mild-to-moderate severity.Only the patients receiving the highest intranasal doses had mild-to-moderate disease. Clinical symptoms were typical for flu, including headache, fatigue, nasal and sinus congestion, rhinorrhea, and sore throat. Symptoms peaked on day 3, with most shedding occurring 1 to 2 days after challenge. Only 10 patients (29%) had a fourfold or greater rise in hemagglutinin inhibition antibody titer after challenge.Compared with an earlier 2009 H1N1 challenge study, the H3N2 trial caused fewer mild-to-moderate symptoms and less shedding, though the incidence of symptoms was similar. The investigators said the fewer anti hemagglutinin antibody responses that they observed, taken together with less mild-to-moderate disease, suggests that other preexisting immunity factors may limit shedding in healthy volunteers.The team wrote that a percentage of people with low hemagglutinin inhibition antibody titers who are unprotected may not develop antibody response to current or future HA-based vaccines and could be a factor in vaccine failure, a phenomenon seen both H1N1 and H3N2 infections. “In addition, these individuals may have other pre-challenge protective immune correlates that were not assessed,” they added. The authors noted that antibodies against neuraminidase were less variable, a finding seen now in both H1N1 and H3N2 human infection models.”Significant questions remain that should be addressed in future challenge studies with this virus and other influenza viruses regarding what aspects of immunity are the most protective, including antibodies against the NA, T-cell immunity, mucosal immunity, and other factors that are potentially playing a very important role in protection,” they wrote.Feb 16 Clin Infect Dis abstract
It also said that prices dropped by 1.3% in April compared with the previous month.The price of the average home is down to £189,027 and the lender said it now expected a “mid-single-digit” percentage decline in prices in 2008. Halifax’s chief economist, Martin Ellis, said the decline in prices was driven by a squeeze on consumers’ spending power and the rapid rise in house prices in the last few years. ‘Completed property sales in March were down 20% on an annual basis,’ he told the BBC. ‘The number of new buyers interested in home purchase fell for the sixteenth successive month in March, highlighting the decline in housing demand,’ he added. According to the Halifax’s figures, prices have fallen by 4.2% in the first four months of the year. If that rate of decline continues for the rest of 2008 then the annual fall in prices will be nearly 13% by the end of the year. The Halifax said it expects bigger falls in Wales and the West Midlands, with Scotland bucking the trend with a modest rise.